Photoinduced Electron Transfer Across Phospholipid Bilayers in Anaerobic and Aerobic Atmospheres

Author(s)

Novitasari Sinambela, Richard Jacobi, Dieter Sorsche, Leticia González, Andrea Pannwitz

Abstract

In natural photosynthesis, light-driven electron transfer across the thylakoid membrane enables efficient charge separation and the confinement of reaction spaces for generating NADPH and CO2 and oxidation of water. These reactions are complementary redox reactions and require different reaction conditions for optimal performance. However, current artificial photosynthesis studies only take place in the bulk and are sensitive toward oxygen and air, which limits their applicability under aerated and water-splitting conditions. Herein, we report light-driven electron transfer across a lipid bilayer membrane of liposome vesicles via a rigid oligoaromatic molecular wire that allows to electronically connect an oxidation and reduction reaction which are spatially separated by the membrane. The molecular wire has a simple, symmetric, easy-to-synthesize design based on benzothiadiazole and fluorene units and absorbs in the visible spectrum which makes it suitable for solar energy conversion. The model reactions in this study are light-driven NADH oxidation on one side of the membrane and light-driven reduction of an organic water-soluble dye in the bulk phase of liposomes. Additionally, the system is active in both aerobic and anaerobic atmospheres, rendering it ideal for aerobic conditions or reactions that produce oxygen such as solar-driven water splitting and artificial photosynthesis applications.

Organisation(s)

Department of Theoretical Chemistry, Research Platform Accelerating Photoreaction Discovery

External organisation(s)

Universität Ulm, Vienna Doctoral School in Chemistry (DoSChem), Friedrich-Schiller-Universität Jena

Journal

Angewandte Chemie (International ed. in English)

Volume

64

Pages

e202423393

ISSN

1433-7851

DOI

https://doi.org/10.1002/anie.202423393

Publication date

03-2025

Peer reviewed

Yes

Austrian Fields of Science 2012

104017 Physical chemistry, 103006 Chemical physics

Keywords

ASJC Scopus subject areas

General Chemistry, Catalysis

Sustainable Development Goals

SDG 7 - Affordable and Clean Energy

Portal url

https://ucrisportal.univie.ac.at/en/publications/c3b4c348-4bb0-43ab-8717-dde73d68cf9f